BEXTRA NEWS & PRESCRIPTIONS DRUG UPDATES

FOLLOWING BEXTRA RECALL PATIENTS SWITCHING TO OTHER PRESCRIPTIONS
Genetic Engineering News, 04/13/2005
"Over 10,000 projected patients within the arthritis market, representing 47.6% of the switches away from Bextra, switched to NSAIDs. Another 24.5% of patients switched to the branded NSAID Mobic, co-marketed by Boehringer Ingelheim and Abbott Laboratories. Celebrex, Pfizer's older COX-2 inhibitor, received 24.2% of the business previously held by Bextra."

PAINKILLER DECISIONS SUGGESTS SHIFT IN FDA'S RISK-BENEFIT EQUATION
The Washington Post, 04/11/2005
"Certain drug risks that used to be acceptable to the agency have become unacceptable, and benefits that usually guaranteed approval of a new drug are no longer a sure bet -- but whether that is good or bad depends on an observer's viewpoint."

NEW LABELING FOR PFIZER'S CELEBREX AND OTHER NSAIDs
I-Newswire.com, 04/11/2005
"Pfizer said today it will work with the U.S. Food and Drug Administration (FDA) to add expanded risk information in the Celebrex label following an FDA decision announced this morning to require boxed warnings of potential cardiovascular risk for all COX-2 pain relievers and all NSAIDs, including older non-specific drugs such as ibuprofen and naproxen."

MICHIGAN DEMS WANT TO REPEAL MICHIGAN LAW THAT PROTECTS DRUG MAKERS - Wood TV - MI, 04/11/2005
"It's something severely limited under existing law, but Democrats in the state House think residents hurt by a prescription medication should be able to sue drug makers for damages.

Democrats are expected to announce Monday a package of legislation repealing the 1996 law that shields drug makers from liability if the Food and Drug Administration approved their product."

FDA: PFIZER TO PUT WARNING ON CELEBREX DRUG, PULL BEXTRA
St. Louis Business Journal, 04/07/2005
"The Food and Drug Administration asked Pfizer Inc. to take its Bextra prescription pain reliever off the market and include a boxed warning on its Celebrex drug, the FDA said Thursday."

If you are currently taking Bextra, you should immediately contact your doctor to discuss alternative medication. Any decision about which drug product to take to treat your symptoms should be made in consultation with your physician based on an assessment of your specific treatment needs.

If you have been injured by Bextra the manufacturer may have failed in its duty to design, make, inspect and label the product appropriately.

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